Cleerly Heart Test: The Future of Cardiovascular Prevention

Cardiovascular disease remains the number one cause of death globally, with nearly 700,000 Americans dying from heart-related conditions each year, according to the CDC. Many of these events are sudden, occurring in individuals with no prior symptoms. Traditional diagnostic methods like EKGs, cholesterol panels, and the calcium scan have served us for decades, but they often miss critical, early indicators of risk. That’s where Cleerly—a groundbreaking, FDA-cleared technology—comes in.

At Gentera Center for Precision Medicine in Coral Gables, we’re redefining heart health through the Cleerly heart scan, offering patients a precise, personalized, and preventative solution to cardiovascular risk.

What Is the Cleerly Heart Test?

The Cleerly heart test is a non-invasive coronary analysis that uses advanced AI to evaluate a coronary CT angiography (CCTA) scan. Unlike a standard calcium scan—which only shows calcified plaque—Cleerly offers a detailed 3D model of your heart’s arteries and identifies:

• Total plaque volume
• Types of plaque (fibrous, calcified, or lipid-rich)
• Degree of artery narrowing (stenosis)
• Areas of inflammation and ischemia
• Risk factors for plaque rupture

This allows your physician to diagnose not just existing blockages, but also early soft plaque, which is the most likely to rupture and cause a heart attack.

Calcium Scan vs. Cleerly: What’s the Difference?

Many patients are familiar with the coronary artery calcium scan (CAC), often referred to simply as a calcium scan. It’s a useful screening tool that measures hardened plaque in the arteries. However, it misses soft plaque and does not evaluate the risk of future rupture, which is where the real danger lies.

The Cleerly heart scan, in contrast:

• Detects both calcified and soft plaque
• Measures total plaque volume
• Visualizes artery narrowing (stenosis)
• Offers AI-powered precision analysis
• Predicts future cardiac events with higher accuracy

Who Should Get a Cleerly Heart Scan?

The Cleerly test is ideal for people who:

• Have a family history of heart disease
• Are over the age of 40
• Have elevated cholesterol, high blood pressure, or diabetes
• Have experienced abnormal EKGs or borderline CAC scores
• Want more clarity than a calcium scan Coral Gables clinics typically offer
• Are enrolled in concierge or longevity-focused health programs
• Even people with normal cholesterol levels or no symptoms can have dangerous levels of soft plaque. The Cleerly heart scan helps uncover those hidden risks.

Understanding Severe Coronary Artery Calcification

Severe coronary artery calcification is a major red flag. Studies show that patients with high calcium scores have a significantly increased risk of cardiac events over 10 years. But even those with low calcium scores may carry dangerous soft plaque.

Cleerly’s ability to detect both hard and soft plaque—and quantify the total burden—makes it a game changer in preventing sudden cardiac death. A 2022 JACC study found that Cleerly’s AI platform provided 98% sensitivity in detecting high-risk plaque compared to invasive angiography (Bittencourt et al., 2022).

How Cleerly Works

The Cleerly heart scan process at Gentera is simple, fast, and non-invasive:

1. Coronary CT Angiography (CCTA) is performed using advanced imaging.
2. The scan is uploaded to Cleerly’s cloud-based AI platform.
3. Cleerly’s proprietary algorithms generate a detailed report and 3D artery model.
4. Your physician at Gentera reviews your personalized heart report and creates a tailored action plan.
5. The entire process takes under an hour, requires no sedation, and provides peace of mind backed by data.

Why Gentera Uses Cleerly

At Gentera Med, we believe in precision medicine with purpose. By detecting cardiovascular threats earlier, we can help you take action—whether that’s through lifestyle changes, peptide therapies, or medication protocols designed to stabilize plaque and reduce inflammation.

Our integration of Cleerly into your care plan ensures:

• More accurate cardiovascular risk stratification
• Personalized prevention plans
• Monitoring of plaque regression or progression
• Support for proactive longevity-focused care
• Clinical Studies Supporting Cleerly

Several studies validate the power of Cleerly:

• Bittencourt et al., 2022 (JACC): Demonstrated 98% sensitivity in plaque detection.
• ROMICAT-II Trial: Proved CCTA’s role in efficient ER triage.
• PRECISE Trial (2023): Showed Cleerly-guided care reduces unnecessary catheterizations.
• These findings confirm that AI-enhanced CCTA like Cleerly not only improves diagnosis but enhances patient outcomes.

Cleerly and Concierge Medicine at Gentera

If you’re part of Gentera’s Concierge Medicine program, your Cleerly scan is more than a one-time screening. It’s integrated into your annual health optimization strategy, allowing your physician to:

• Track changes in plaque volume over time
• Adjust therapies based on imaging results
• Optimize cardiovascular function year-round

This is medicine made for people who want to live longer—and better.

Schedule Your Cleerly Heart Scan in Coral Gables

Your heart deserves clarity. Don’t rely solely on cholesterol numbers or outdated screening tools. If you’re looking for a smarter, more personalized way to assess your cardiovascular health, the Cleerly heart test is it.

Now available at Gentera Center for Precision Medicine — Coral Gables.

Book your Cleerly heart scan today.

References

• Bittencourt, M. S., et al. (2022). “Artificial Intelligence Analysis of Coronary CTA for Plaque Quantification and Risk Prediction.” Journal of the American College of Cardiology (JACC).
• American Heart Association. (2023). Heart Disease and Stroke Statistics. https://www.heart.org
• Cleerly Inc. (2024). Product Overview and Clinical Trials. https://www.cleerlyhealth.com